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Recombinant Human TGF-beta 2 (Carrier-free)

Recombinant Human TGF-beta 2 (Carrier-free)

Item no.	21-8478-U010
Manufacturer	Tonbo Biosciences
Amount	10 ug
Category	Oncology Neuroscience Neural Signaling Peptides & Proteins Recombinant Proteins By Organ Colorectal Cancer
Type	Proteins Recombinant
Specific against	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Description	Transforming Growth Factor beta 2 (TGF-beta 2) is a member of the TGF superfamily, and exists alongside 2 other mammalian isoforms of TGF-beta - TGF-beta 1 and TGF-beta 3 - which share a pair of receptors. All three isoforms are secreted by most cell types, and for regulatory control, must be activated before they exert functional activity. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility, as well as synthesis and deposition of the extracellular matrix. TGF-beta2 can induce differentiation, apoptosis, and angiogenesis.
Alternative Names	Transforming Growth Factor-beta2, Glioblastoma-derived T cell suppressor factor, BSC-1, Cetermin, Polyergin
Amino Acid Sequence	ALDAAYCFRN VQDNCCLRPL YIDFKRDLGW KWIHEPKGYN ANFCAGACPY LWSSDTQHSR VLSLYNTINP EASASPCCVS QDLEPLTILY YIGKTPKIEQ LSNMIVKSCK CS
Authenticity	Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity	Determined by its ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The ED₅₀ was found to be ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 10⁶ units/mg.
Endotoxin Level	Endotoxin level is < 0.1 ng/µ g of protein ( < 1EU/µ g).
Molecular Mass	Recombinant human TGF-beta 2 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
Protein Content	Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Research Areas	Angiogenesis/Cardiovascular; Apoptosis; Cancer; Immune System; Inflammation; Proliferation; Stem Cells & Differentiation; TGF-beta Superfamily; Wound Healing; Allergy
Purity	98%
Reconstitution	See Certificate of Analysis (COA) for lot specific reconstitution information.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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