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Recombinant Human GM-CSF (Carrier-free)

Recombinant Human GM-CSF (Carrier-free)

Item no.	21-8339-U005
Manufacturer	Tonbo Biosciences
Amount	5 ug
Category	Neuroscience Neural Signaling Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Description	Human GM-CSF, along with other colony stimulating factors, are key drivers of differentiation and proliferation of hematopoietic precursors. GM-CSF increases leukocyte and reticulocyte counts and also recruits eosinophils, macrophages and neutrophils to sites of inflammation. GM-CSF is secreted by macorphages, mast cells, T cells, NK cells, endothelial cells and fibroblasts. Because of its potent ability to mobilize white blood cells, GM-CSF is used therapeutically to stimulate white blood cell production following chemotherapy.
Amino Acid Sequence	MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE
Authenticity	Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity	The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.
Endotoxin Level	Endotoxin level is < 0.1 ng/µ g of protein ( < 1EU/µ g).
Molecular Mass	Recombinant Human GM-CSF is a 14.6 kDa protein consisting of 128 amino acids.
Protein Content	Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Research Areas	Cancer; Cell Culture; Inflammation; Proliferation; Stem Cells & Differentiation; Wound Healing
Purity	98%
Reconstitution	See Certificate of Analysis (COA) for lot specific reconstitution information.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 ug

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