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violetFluor™ 450 Anti-Mouse CD45 (30-F11)

violetFluor™ 450 Anti-Mouse CD45 (30-F11)

Item no.	75-0451-U025
Manufacturer	Tonbo Biosciences
Amount	25 ug
Category	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Hematology Leukemia Flow Cytometry Primary Antibodies Progenitor Markers
Type	Antibody Monoclonal
Format	vFluor 450
Applications	FC
Clone	30-F11
Specific against	Mouse
Host	Rat
Isotype	IgG2b kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Leukocyte Common Antigen, LCA, Ly-5
Similar products	30-F11
Available
Description	The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others. The 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets.
Alternative Names	Leukocyte Common Antigen, LCA, Ly-5
Gene ID	19264
Citations	Panchal RG, Ulrich RL, Bradfute SB, Lane D, Ruthel G, Kenny TA, Iversen PL, Anderson AO, Gussio R, Raschke WC, and Bavari S. 2009. 284: 12874-12885. (Immunoprecipitation) Cherpes TL, Busch JL, Sheridan BS, Harvey SAK, and Hendricks RL. 2008. J. Immunol. 181: 969-975. (Complement-mediated cell depletion) Cheng G, Zhang H, Yang X, Tzima E, Ewalt KL, Schimmel P, and Faber JE. 2008. Am. J. Physiol. Regul. Integr. Comp. Physiol. 295: R1138-R1146. (Immunohistochemistry - paraffin embedded tissue) Nguyen JT, Evans DP, Galvan M, Pace KE, Leitenberg D, Bui TN, and Baum LG. 2001. J. Immunol. 167: 5697-5707. (Immunofluorescence microscopy, Immunoprecipitation) Czyzyk J, Leitenberg D, Taylor T, and Bottomly K. 2000. Mol. Cell. Biol. 20(23): 5740-5747. (Western Blot) Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273: 30680-30687. (Western Blot)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 ug

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Delivery expected until 9/6/2024

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