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Biotin Anti-Mouse IFN gamma (XMG1.2)

Biotin Anti-Mouse IFN gamma (XMG1.2)

Manufacturer	Tonbo Biosciences
Category	Neuroscience Neuroinflammation Antibodies Cell Biology Cell Culture Cytokines Flow Cytometry Primary Antibodies
Type	Antibody
Specific against	Mouse
Clone	XMG1.2
Isotype	IgG1 kappa
Format	Biotin
Applications	FC, ELISA
Amount	25 ug
Host	Rat
Item no.	30-7311-U025
Targets	IFNG
Conjugate/Tag	Biotin
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	IFN-g, IFNg, Interferon-g, Immune interferon, Type II interferon, T cell interferon, Macrophage-activating factor (MAF)
Description	The XMG1.2 antibody is specific for mouse Interferon-gamma (IFN-g), a 20 kDa type II cytokine known for its central roles in protection against bacterial or viral pathogens and for its anti-tumor properties. IFN-g is secreted by several types of immune cells which allow the cytokine to modulate innate immunity when secreted by NK and NKT cells, and to function in support of adaptive immunity when secreted by Th1 and CD8+ T cells (CTLs). The XMG1.2 antibody is suitable for detection of intracellular IFN-g protein by flow cytometry. This format can be used for quantitative analysis of the secreted protein by ELISA when paired with an appropriate capture antibody. This clone has been reported for neutralization of the functional activity of IFN-g in a variety of assays (use format suitable for functional assays).
Alternative Names	IFN-g, IFNg, Interferon-g, Immune interferon, Type II interferon, T cell interferon, Macrophage-activating factor (MAF)
Gene ID	15978
Citations	Choudhry N, Petry F, van Rooijen N, and McDonald V. 2012. J. of Infect. Disease. 206: 117-124. (in vivo neutralization) Cobb D and Smeltz RB. 2012. J. Immunol. 188: 3766-3773. (in vitro neutralization) Brown DM, Lee S, Garcia-Hernandez M, and Swain SL. 2012. J. Virol. 86: 6792-6803. (ELISpot - detection) Yu H, Karunakaran KP, Jiang X, Shen C, Andersen P, and Brunham RC. 2012. Infect. Immun. 80: 1510-1518. (ELISpot -detection) Kwon M-J, Ma J, Ding Y, Wang R, and Sun Z. 2012. J. Immunol. 188: 5887-5897. (in vitro induction of Th2 polarization) Barr TA, Shen P, Brown S, Lampropoulou V, Roch T, Lawrie S, Fan B, O´ Connor RA, Anderton SM, Bar-Or Am Fillatreau S, and Gray D. 2012. J. Exp. Med. 209: 1001-1010. (Flow cytometry) Cardona AE, Restrepo BI, Jaramillo JM, and Teale JM. 1999. J. Immunol. 162: 995-1002. (Immunohistochemistry - frozen tissue) Kupfer A, Mosmann TR, and Kupfer H. 1991. Proc. Natl. Acad. Sci. 88: 775-779. (Immunofluorescence microscopy)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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