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CCT245737

CCT245737

Item no.	TMO-T7080-25mg
Manufacturer	TargetMol
CASRN	1489389-18-5
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,98
Citations	1. Osborne JD, et al. Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinicalal Candidate: (R)-5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737). J Med Chem. 2016 Jun 9;59(11):5221-37.
Smiles	FC(F)(F)c1cnc(Nc2cnc(cn2)C#N)cc1NC[C@H]1CNCCO1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Chk inhibitor, SRA737
Available
Short Description	CCT245737 is an orally active and selective Chk1 inhibitor (IC50: 1.3 nM); CCT245737 shows much less activity against Chk2 (IC50: 2440 nM).
Shipping	cool pack
Storage	-20°
Target names or alias	SRA737
Molecular Weight	379, 34
Pathway	Cell Cycle/Checkpoint
Target	Chk

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25mg

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Delivery expected until 9/20/2024

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