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PD168393

PD168393

Item no.	TMO-T6932-2mg
Manufacturer	TargetMol
CASRN	194423-15-9
Amount	2mg
Category	Oncology Neuroscience Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Neural Signaling Reagents & Chemicals Molecules By Organ Bladder Cancer
Type	Molecules
Specific against	other
Citations	1. Fry DW,et al. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):12022-7.
Smiles	C=CC(=O)Nc1cc2c(cc1)ncnc2Nc1cc(ccc1)Br
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Short Description	PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.
Shipping	cool pack
Storage	-20°
Molecular Weight	369, 22
Pathway	Angiogenesis\|\|\|Autophagy\|\|\|Tyrosine Kinase/Adaptors\|\|\|Cytoskeletal Signaling\|\|\|Apoptosis\|\|\|JAK/STAT signaling\|\|\|Chromatin/Epigenetic
Target	Autophagy\|\|\|IGF-1R\|\|\|PKC\|\|\|PDGFR\|\|\|EGFR\|\|\|FGFR\|\|\|Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 2mg

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Delivery expected until 9/27/2024

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