Comparison

AT101 acetate European Partner

Item no. TMO-T6396-5mg
Manufacturer TargetMol
CASRN 866541-93-7
Amount 5mg
Category
Type Molecules
Specific against other
Purity 0,98
Citations 1. Wang G, et al. J Med Chem. 2006, 49(21), 6139-6142.
Smiles CC(O)=O.CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias (R)-Gossypol acetic acid , (-)-Gossypol acetic acid , AT-101 (acetic acid) , AT101 acetate , AT101
Available
Short Description
AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM; does not inhibit BIR3 domain and BID. Phase 2.
Shipping
cool pack
Storage
-20°
Target names or alias
(R)-Gossypol acetic acid , (-)-Gossypol acetic acid , AT-101 (acetic acid) , AT101 acetate , AT101
Molecular Weight
578, 61
Pathway
Apoptosis|||Autophagy
Target
Autophagy|||BCL

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5mg
Available: In stock
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