Comparison

BMS202 hydrochloride (1675203-84-5(free base)) European Partner

Item no. TMO-T4696-2mg
Manufacturer TargetMol
CASRN 2089334-95-0
Amount 2mg
Category
Type Molecules
Specific against other
Purity 0,98
Citations 1.Zak KM, Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1).Oncotarget. 2016 May 24;7(21):30323-35.
Smiles Cl.COc1nc(OCc2cccc(c2C)-c2ccccc2)ccc1CNCCNC(C)=O
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias PD-1/PD-L1, PD-1/PD-L1 inhibitor 2 hydrochloride
Available
Short Description
PD-1/PD-L1 inhibitor 2 is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction.
Shipping
cool pack
Storage
-20°
Target names or alias
PD-1/PD-L1 inhibitor 2 hydrochloride
Molecular Weight
455, 97
Pathway
Cell Cycle/Checkpoint|||Immunology/Inflammation|||Apoptosis
Target
PD-1/PD-L1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 2mg
Available: In stock
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