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YHO13177

YHO13177

Item no.	TMO-T4595-25mg
Manufacturer	TargetMol
CASRN	912287-56-0
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9864
Citations	1.Yamazaki R, et al. Novel acrylonitrile derivatives, YHO-13177 and YHO-13351, reverse BCRP/ABCG2-mediated drug resistance in vitro and in vivo. Mol Cancer Ther. 2011 Jul;10(7):1252-63.
Smiles	COc1ccc(cc1OC)C(\C#N)=C\c2ccc(s2)N3CCC(O)CC3
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	YHO13177 , YHO 13177
Available
Short Description	YHO-13177 is a potent and specific inhibitor of BCRP; potentiated the cytotoxicity of SN-38 in cancer cells and no effect on P-glycoprotein–mediated paclitaxel resistance in MDR1-transduced human leukemia K562 cells.
Shipping	cool pack
Storage	-20°
Target names or alias	YHO13177 , YHO 13177
Molecular Weight	370, 47
Pathway	Membrane transporter/Ion channel
Target	BCRP

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25mg

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Delivery expected until 8/23/2024

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