Comparison

MS049 2HCl (1502816-23-0(free base)) European Partner

Item no. TMO-T4393-200mg
Manufacturer TargetMol
CASRN 1502816-23-0(free base)
Amount 200mg
Category
Type Molecules
Specific against other
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias Histone Methyltransferase inhibitor
Available
Bioactivity

MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM). It is less active against additional type I PRMTs (IC50s = >, 130, >, 220, and 1.6 uM for PRMT1, PRMT3, and PRMT8, respectively) and displays no inhibition against type II or type III PRMTs nor any additional methyltransferases or nonepigenetic targets tested.

Mol wt.
321, 28
Pathways
Chromatin/Epigenetic
Receptor
PRMT4, PRMT6

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200mg
Available: In stock
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