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PF-3758309 hydrochloride

PF-3758309 hydrochloride

Item no.	TMO-T4230-25mg
Manufacturer	TargetMol
CASRN	1279034-84-2
Amount	25mg
Category	Oncology Neuroscience Targets for Rodent Neurosciences Reagents & Chemicals Molecules By Organ Lung Cancer
Type	Molecules
Specific against	other
Citations	1. Briz V, Baudry M. Estrogen Regulates Protein Synthesis and Actin Polymerization in Hippocampal Neurons through Different Molecular Mechanisms. Front Endocrinol (Lausanne). 2014 Feb 25;5:22. doi: 10.3389/fendo.2014.00022. eCollection 2014. PubMed PMID: 24611062; PubMed Central PMCID: PMC3933789.
Smiles	Cl.CN(C)C[C@@H](NC(=O)N1Cc2c(Nc3nc(C)nc4ccsc34)n[nH]c2C1(C)C)c1ccccc1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	PAK inhibitor, PF-03758309 hydrochloride
Available
Short Description	PF-3758309, also known as PF-03758309, is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PAK4 inhibitor PF-03758309 binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival.
Shipping	cool pack
Storage	-20°
Target names or alias	PF-03758309 hydrochloride
Molecular Weight	527, 08
Pathway	Apoptosis\|\|\|Cytoskeletal Signaling
Target	Apoptosis\|\|\|PAK

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25mg

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Delivery expected until 8/23/2024

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