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Vaccarin

Vaccarin

Item no.	TMO-T3881-10mg
Manufacturer	TargetMol
CASRN	53452-16-7
Amount	10mg
Category	Neuroscience Neuroinflammation Neural Signaling Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Xie F,et al. Vaccarin promotes endothelial cell proliferation in association with neovascularization in vitro and in vivo. Mol Med Rep. 2015 Jul;12(1):1131-6.
Smiles	C1[CH]([CH]([CH]([CH](O1)O[CH]2[CH]([CH]([CH](O[CH]2C3=C(C=C4C(=C3O)C(=O)C=C(O4)C5=CC=C(C=C5)O[CH]6[CH]([CH]([CH]([CH](O6)CO)O)O)O)O)CO)O)O)O)O)O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Akt activator; ERK; Integrin
Available
Bioactivity	Vaccarin is a major flavonoid glycoside in Vaccariae semen, its biotransformation pathways involves methylation, hydroxylation, glycosylation and deglycosylation. Vaccarin can significantly promote neovascularization by enhancing protein expression of p-Akt , p?Erk, and CD31. Vaccarin may be able to selectively protect vascular endothelium from dysfunction induced by H2O2.
MolWt	726, 637
Pathways	Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
Receptor	P-Akt; PERK; CD31

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10mg

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Delivery expected until 8/16/2024

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