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Lasmiditan

Lasmiditan

Item no.	TMO-T3704-100mg
Manufacturer	TargetMol
CASRN	439239-90-4
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Nelson DL, et al. Cephalalgia. 2010 Oct;30(10):1159-69.
Smiles	CN1CCC(CC1)C(=O)C2=NC(=CC=C2)NC(=O)C3=C(C=C(C=C3F)F)F
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	5-HT Receptor agonist
Available
Bioactivity	Lasmiditan, also known as COL-144 and LY573144, is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (K1=2.21 uM) without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof-of-concept migraine study. Lasmiditan showed efficacy in its primary endpoint, with a 2-hour placebo-subtracted headache response of 28.8%, though with frequent reports of dizziness, paresthesias, and vertigo.
MolWt	377, 14
Pathways	GPCR/G Protein; Neuroscience
Receptor	5-HT1F

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100mg

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Delivery expected until 9/20/2024

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