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Ruboxistaurin hydrochloride

Ruboxistaurin hydrochloride

Item no.	TMO-T3689-1mg
Manufacturer	TargetMol
CASRN	169939-93-9
Amount	1 mg
Quantity options	100 mg 10 mM x 1 mL (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9597
Citations	1. Faul MM, et al. Bioorg Med Chem Lett. 2003 Jun 2;13(11):1857-9.
Smiles	Cl.CN(C)CC1CCn2cc(C3=C(C(=O)NC3=O)c3cn(CCO1)c1ccccc31)c1ccccc21
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	LY 333531 hydrochloride, LY333531 HCl, Ruboxistaurin
Shipping condition	Cool pack
Available
Manufacturer - Targets	PKC
Shipping Temperature	cool pack
Storage Conditions	-20°
Molecular Weight	505, 01
Target names or alias	LY333531 HCl , LY 333531 hydrochloride , Ruboxistaurin
Description	Ruboxistaurin hydrochloride (LY 333531 hydrochloride) is an Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCβI and PKCβII (IC50 values are 4.7 and 5.9 nM respectively). Selective for PKCβ over other PKC isozymes (IC50values are 0.052, 0.25, 0.30, 0.36, 0.60 and >100 μM for PKCη, -δ, -γ, -α, -ε and -ζ respectively). Exhibits selectivity for PKC over other ATP-dependent kinases, including protein kinase A, casein kinase and src).
Pathways	Cytoskeletal Signaling\|\|\|Chromatin/Epigenetic

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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