Comparison

Ruboxistaurin hydrochloride European Partner

Item no. TMO-T3689-1mg
Manufacturer TargetMol
CASRN 169939-93-9
Amount 1mg
Category
Type Molecules
Specific against other
Purity 0,9597
Citations 1. Faul MM, et al. Bioorg Med Chem Lett. 2003 Jun 2;13(11):1857-9.
Smiles CN(C)C[C@@H]1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O.Cl
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias PKC inhibitor, LY333531 HCl , LY 333531 hydrochloride , Ruboxistaurin
Available
Short Description
Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCβI and PKCβII (IC50 values are 4.7 and 5.9 nM respectively). Selective for PKCβ over other PKC isozymes (IC50values are 0.052, 0.25, 0.30, 0.36, 0.60 and >100 μM for PKCη, -δ, -γ, -α, -ε and -ζ respectively). Exhibits selectivity for PKC over other ATP-dependent kinases, including protein kinase A, casein kinase and src).
Shipping
cool pack
Storage
-20°
Target names or alias
LY333531 HCl , LY 333531 hydrochloride , Ruboxistaurin
Molecular Weight
505, 01
Pathway
Chromatin/Epigenetic|||Cytoskeletal Signaling
Target
PKC

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1mg
Available: In stock
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