Comparison

Ruboxistaurin hydrochloride European Partner

Item no. TMO-T3689-10mM
Manufacturer TargetMol
CASRN 169939-93-9
Amount 10mM*1mL(inDMSO)
Category
Type Molecules
Specific against other
Citations 1. Faul MM, et al. Bioorg Med Chem Lett. 2003 Jun 2;13(11):1857-9.
Smiles CN(C)C[CH]1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O.Cl
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias PKC inhibitor
Available
Bioactivity
Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCbetaI and PKCbetaII (IC50 values are 4.7 and 5.9 nM respectively). Selective for PKCbeta over other PKC isozymes (IC50values are 0.052, 0.25, 0.30, 0.36, 0.60 and >100 uM for PKCeta, -delta, -gamma, -alpha, -epsilon and -zeta respectively). Exhibits selectivity for PKC over other ATP-dependent kinases, including protein kinase A, casein kinase and src).
MolWt
505, 01
Pathways
Cytoskeletal Signaling
Receptor
PKCbeta1; PKCbeta2; PKCgamma; PKCdelta; PKCeta

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10mM*1mL(inDMSO)
Available: In stock
available

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