FIIN3

Item no.	TMO-T3466-10mM
Manufacturer	TargetMol
CASRN	1637735-84-2
Amount	10mM*1mL(inDMSO)
Category	Oncology Neuroscience Neural Lineage Markers Neural Adhesion Molecules Reagents & Chemicals Molecules By Organ Colorectal Cancer Calcium Binding Protein Markers Interneuron Markers
Type	Molecules
Specific against	other
Citations	1.Tan L et al. Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors. Proc Natl Acad Sci U S A, 2014 Nov 11, 111(45):E4869-77
Smiles	CN1CCN(CC1)C2=CC=C(C=C2)NC3=CC(=NC=N3)N(CC4=CC=C(C=C4)NC(=O)C=C)C(=O)NC5=C(C(=CC(=C5Cl)OC)OC)Cl
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	FGFR inhibitor
Available
Bioactivity	FIIN-3 is an irreversible inhibitor of FGFR1-4 with IC50s of 13, 21, 31, and 35 nM, respectively.
MolWt	691, 614
Pathways	Angiogenesis; Tyrosine Kinase/Adaptors
Receptor	FGFR1; FGFR2; FGFR3; FGFR4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10mM*1mL(inDMSO)

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