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PF04418948

PF04418948

Item no.	TMO-T3306-10mg
Manufacturer	TargetMol
CASRN	1078166-57-0
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,98
Smiles	C(C1(CN(C1)C(=O)c1ccc(cc1)F)C(=O)O)Oc1cc2c(cc(OC)cc2)cc1
ECLASS 5.1	32169090
ECLASS 6.1	32169090
ECLASS 8.0	32169090
ECLASS 9.0	32169090
ECLASS 10.0.1	32169090
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	PF 04418948 , PF04418948
Available
Short Description	PF-04418948 is a potent EP2 receptor antagonist (IC50 = 16 nM for human EP2 receptors). Displays over 2000-fold selectivity for EP2 receptors over EP1, EP3, EP4, DP1 amd CRTH2 receptors; exhibits <30% binding at a diverse panel of GPCRs and ion channels at a concentration of 10 μM. Inhibits PGE2-induced increases in intracellular cAMP; reverses PGE2-invoked relaxation of mouse trachea (IC50 = 2.7 nM).
Shipping	cool pack
Storage	-20°
Target names or alias	PF 04418948 , PF04418948
Molecular Weight	409, 41
Pathway	GPCR/G Protein\|\|\|Immunology/Inflammation
Target	Prostaglandin Receptor

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10mg

available

Delivery expected until 8/2/2024