Comparison

Dactolisib European Partner

Item no. TMO-T2235-25mg
Manufacturer TargetMol
CASRN 915019-65-7
Amount 25mg
Category
Type Molecules
Specific against other
Citations 1. Maira SM, et al. Mol Y Ther, 2008, 7(7), 1851-1863.2. Roper J, et al. PLoS One, 2011, 6(9), e25132.
Smiles Cn1c2cnc3ccc(cc3c2n(-c2ccc(cc2)C(C)(C)C#N)c1=O)-c1cnc2ccccc2c1
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias NVP-BEZ235 , BEZ235
Available
Short Description
Dactolisib is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).
Shipping
cool pack
Storage
-20°
Target names or alias
NVP-BEZ235 , BEZ235
Molecular Weight
469, 54
Pathway
PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair|||Autophagy
Target
PI3K|||Autophagy|||ATM/ATR|||mTOR

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25mg
Available: In stock
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