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2-Methoxyestradiol

2-Methoxyestradiol

Manufacturer	TargetMol
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Amount	200mg
Item no.	TMO-T2220-200mg
CASRN	362-07-2
eClass 6.1	32169090
eClass 9.0	32169090
Available
Alias	HIF inhibitor; Microtubule Associated inhibitor
Purity	0,9984
Bioactivity	2-Methoxyestradiol is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endothelial cell apoptosis. This agent also inhibits tumor cell growth by binding to tubulin, resulting in antimitotic activity, and by inducing caspase activation, resulting in cell cycle arrest in the G2 phase, DNA fragmentation, and apoptosis.
MolWt	302, 41
Pathways	Angiogenesis; Cytoskeletal Signaling; Chromatin/Epigenetic
Receptor	HIF-1alpha; HIF-2alpha; Microtubule depolymerization

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Amount: 200mg

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Delivery expected until 7/19/2024

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