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Clozapine

Clozapine

Item no.	TMO-T0455-100mg
Manufacturer	TargetMol
CASRN	5786-21-0
Amount	100 mg
Quantity options	100 mg 10 mM x 1 mL (in DMSO) 10 mg 1 g 1 mL 200 mg 2 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9991
Citations	1. Brunello N, et al. Neuropsychopharmacology, 1995, 13(3), 177-213.
Smiles	Cl.CN1CCN(CC1)C1=NC2=C(NC3=C1C=CC=C3)C=CC(Cl)=C2
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	LX 100-129, HF 1854
Shipping condition	Cool pack
Available
Manufacturer - Targets	Adrenergic Receptor\|\|\|Dopamine Receptor\|\|\|AChR
Shipping Temperature	cool pack
Storage Conditions	-20°
Molecular Weight	326, 82
Target names or alias	LX 100-129 , HF 1854
Description	Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity.
Pathways	Neuroscience\|\|\|GPCR/G Protein

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