Item no. |
STJ120187-100 |
Manufacturer |
St John's Laboratory
|
Amount |
100 ul |
Category |
|
Type |
Antibody Monoclonal |
Applications |
WB, IHC |
Clone |
4H4 |
Specific against |
Human, Mouse, Rat, Bovine |
Host |
Mouse |
Isotype |
IgG1 |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Anti-Parkinson Disease Protein 7 Homolog antibody</br>Anti-Contraception-Associated Protein 1 antibody</br>Anti-Protein Cap1 antibody</br>Anti-Fertility Protein Sp22 antibody</br>Anti-Maillard Deglycase antibody</br>Anti-Parkinsonism-Associated Deglycase |
Similar products |
Anti-Parkinson Disease Protein 7 Homolog antibodyAnti-Contraception-Associated Protein 1 antibodyAnti-Protein Cap1 antibodyAnti-Fertility Protein Sp22 antibodyAnti-Maillard Deglycase antibodyAnti-Parkinsonism-Associated Deglycase |
Available |
|
Clonality |
Monoclonal |
Conjugation |
Unconjugated |
Formulation |
100 ul in PBS + 10 mM NaN3. |
Purification |
This antibody was protein g purified culture from supernatant. |
Uniprot ID |
O88767 |
Storage |
Store at-20° C, and avoid repeated freeze-thaw cycles. |
Description |
Park7, also known as DJ-1, is a member of the peptidase C56 family of proteins and is thought to function as a molecular chaperone. Mutations in park7 have been associated with autosomal recessive, early onset Parkinson’s disease (Bonifati et al., 2003). Recently, park7 has been shown to inhibit microtubule associated protein 1B aggregation thus leading to neuronal apoptosis (Wang et al., 2011). |
Gene ID |
|
Immunogen |
Full length recombinant human Park7 expressed in and purification from E. coli. |
Tissue specificity |
Ubiquitous. Detected on epididymal sperm. Highly expressed in testis and prostate. Detected at lower levels in heart, lung, brain, liver, kidney, seminal vesicle, caput and corpus epididymis. |
Cellular localization |
Cell MembraneLipid-AnchorCytoplasmMembrane RaftNucleusMitochondrionEndoplasmic ReticulumUnder Normal ConditionsLocated Predominantly In The Cytoplasm AndTo A Lesser ExtentIn The Nucleus And MitochondrionTranslocates To The Mitochondrion And Subsequently To The Nucleus In Response To Oxidative Stress And Exerts An Increased Cytoprotective Effect Against Oxidative DamageMembrane Raft Localization In Astrocytes And Neuronal Cells Requires Palmitoylation |
Molecular weight |
21 kDa |
Dilution range |
WB 1:2000; IF 1:500 |
Alternative names |
Anti-Parkinson Disease Protein 7 Homolog antibodyAnti-Contraception-Associated Protein 1 antibodyAnti-Protein Cap1 antibodyAnti-Fertility Protein Sp22 antibodyAnti-Maillard Deglycase antibodyAnti-Parkinsonism-Associated Deglycase antibodyAnti-Protein Dj-1 antibodyAnti-Dj-1 antibodyAnti-Protein/Nucleic Acid Deglycase Dj-1 antibodyAnti-Park7 Cap1 antibody |
Protein name |
Parkinson Disease Protein 7 HomologContraception-Associated Protein 1Protein Cap1Fertility Protein Sp22Maillard DeglycaseParkinsonism-Associated DeglycaseProtein Dj-1Dj-1Protein/Nucleic Acid Deglycase Dj-1 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.