Anti-SHTN1 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

A0MZ66

57698

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SHTN1 (NP_001120683. 1).

Perikaryon
Cell Projection
Axon
Growth Cone
Cytoplasm
Cytoskeleton
Filopodium
Lamellipodium
Localizes In Multiple Growth Cones At Neurite Tips Before The Neuronal Symmetry-Breaking Step
Accumulates In Growth Cones Of A Single Nascent Axon In A Neurite Length-Dependent Manner During The Neuronal Symmetry-Breaking Step
When Absent From The Nascent Axon's Siblings
Probably Due To Competitive Transport
Prevents The Formation Of Surplus Axons
Transported Anterogradely From The Soma To The Axon Growth Cone In An Actin And Myosin-Dependent Manner And Passively Diffuses Back To The Cell Bodies
Colocalized With L1cam In Close Apposition With Actin Filaments In Filopodia And Lamellipodia Of Axonal Growth Cones In Hippocampal Neurons
Exhibits Retrograde Movements In Filopodia And Lamellopodia Of Axonal Growth Cones
Colocalized With Kif20b Along Microtubules To The Tip Of The Growing Cone In Primary Hippocampal Neurons
Recruted To The Growth Cone Of Developing Axon In A Kif20b-And Microtubule-Dependent Manner

WB 1:500-1:2000

Shootin-1
Shootin1

SHOT1_HUMAN