Item no. |
STJ117600-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50 ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Calsyntenin-1 antibody</br>Anti-Alcadein-Alpha antibody</br>Anti-Alc-Alpha antibody</br>Anti-Alzheimer-Related Cadherin-Like Protein antibody</br>Anti-Non-Classical Cadherin Xb31alpha Cleaved Into-Soluble Alc-Alpha antibody</br>Anti-Salc-Alpha-Ctf1-A |
Similar products |
Anti-Calsyntenin-1 antibodyAnti-Alcadein-Alpha antibodyAnti-Alc-Alpha antibodyAnti-Alzheimer-Related Cadherin-Like Protein antibodyAnti-Non-Classical Cadherin Xb31alpha Cleaved Into-Soluble Alc-Alpha antibodyAnti-Salc-Alpha-Ctf1-A |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
O94985 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 29-350 of human CLSTN1 (NP_055759. 3). |
Short Description |
Rabbit polyclonal against CLSTN1 |
Tissue specificity |
Expressed in the brain and, a lower level, in the heart, skeletal muscle, kidney and placenta. Accumulates in dystrophic neurites around the amyloid core of Alzheimer disease senile plaques (at protein level). |
Cellular localization |
Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane ProteinGolgi Apparatus MembraneCell ProjectionNeuron ProjectionCell JunctionSynapsePostsynaptic Cell MembraneNucleusNeurite TipsLocalized In The Postsynaptic Membrane Of Both Excitatory And Inhibitory SynapsesThe Alcicd Fragment Is Translocated To The Nucleus Upon Interaction With Apbb1 |
Molecular weight |
Calculated: 108kDa/109kDa. Observed: 110kDa |
Dilution range |
WB 1:200-1:2000 |
Alternative names |
Anti-Calsyntenin-1 antibodyAnti-Alcadein-Alpha antibodyAnti-Alc-Alpha antibodyAnti-Alzheimer-Related Cadherin-Like Protein antibodyAnti-Non-Classical Cadherin Xb31alpha Cleaved Into-Soluble Alc-Alpha antibodyAnti-Salc-Alpha-Ctf1-Alpha antibodyAnti-C-Terminal Fragment 1-Alpha antibodyAnti-CLSTN1 CS1 KIAA0911 antibody |
Protein name |
Calsyntenin-1Alcadein-AlphaAlc-AlphaAlzheimer-Related Cadherin-Like ProteinNon-Classical Cadherin Xb31alpha Cleaved Into-Soluble Alc-AlphaSalc-Alpha-Ctf1-AlphaC-Terminal Fragment 1-Alpha |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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