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Anti-CLSTN1 antibody (29-350) (STJ117600)

Anti-CLSTN1 antibody (29-350) (STJ117600)

Item no.	STJ117600-50
Manufacturer	St John's Laboratory
Amount	50 ul
Category	Oncology Neuroscience Neural Lineage Markers Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Blastoma Carcinoma Western Blot Primary Antibodies Glial Cell Markers Neuronal Cell Markers
Type	Antibody Polyclonal
Applications	WB
Specific against	Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Calsyntenin-1 antibody</br>Anti-Alcadein-Alpha antibody</br>Anti-Alc-Alpha antibody</br>Anti-Alzheimer-Related Cadherin-Like Protein antibody</br>Anti-Non-Classical Cadherin Xb31alpha Cleaved Into-Soluble Alc-Alpha antibody</br>Anti-Salc-Alpha-Ctf1-A
Similar products	Anti-Calsyntenin-1 antibody Anti-Alcadein-Alpha antibody Anti-Alc-Alpha antibody Anti-Alzheimer-Related Cadherin-Like Protein antibody Anti-Non-Classical Cadherin Xb31alpha Cleaved Into-Soluble Alc-Alpha antibody Anti-Salc-Alpha-Ctf1-A
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	O94985
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants.
Gene ID	22883
Gene symbol	CLSTN1
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 29-350 of human CLSTN1 (NP_055759. 3).
Short Description	Rabbit polyclonal against CLSTN1
Tissue specificity	Expressed in the brain and, a lower level, in the heart, skeletal muscle, kidney and placenta. Accumulates in dystrophic neurites around the amyloid core of Alzheimer disease senile plaques (at protein level).
Cellular localization	Endoplasmic Reticulum Membrane Single-Pass Type I Membrane Protein Golgi Apparatus Membrane Cell Projection Neuron Projection Cell Junction Synapse Postsynaptic Cell Membrane Nucleus Neurite Tips Localized In The Postsynaptic Membrane Of Both Excitatory And Inhibitory Synapses The Alcicd Fragment Is Translocated To The Nucleus Upon Interaction With Apbb1
Molecular weight	Calculated: 108kDa/109kDa. Observed: 110kDa
Dilution range	WB 1:200-1:2000
Alternative names	Anti-Calsyntenin-1 antibody Anti-Alcadein-Alpha antibody Anti-Alc-Alpha antibody Anti-Alzheimer-Related Cadherin-Like Protein antibody Anti-Non-Classical Cadherin Xb31alpha Cleaved Into-Soluble Alc-Alpha antibody Anti-Salc-Alpha-Ctf1-Alpha antibody Anti-C-Terminal Fragment 1-Alpha antibody Anti-CLSTN1 CS1 KIAA0911 antibody
Protein name	Calsyntenin-1 Alcadein-Alpha Alc-Alpha Alzheimer-Related Cadherin-Like Protein Non-Classical Cadherin Xb31alpha Cleaved Into-Soluble Alc-Alpha Salc-Alpha-Ctf1-Alpha C-Terminal Fragment 1-Alpha
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	CSTN1_HUMAN

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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