Item no. |
STJ114634-100 |
Manufacturer |
St John's Laboratory
|
Amount |
100ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Uroplakin-1a antibody</br>Anti-Up1a antibody</br>Anti-Tetraspanin-21 antibody</br>Anti-Tspan-21 antibody</br>Anti-Uroplakin Ia antibody</br>Anti-Upia antibody</br>Anti-Upka antibody</br>Anti-UPK1A TSPAN21 antibody |
Similar products |
Anti-Uroplakin-1a antibodyAnti-Up1a antibodyAnti-Tetraspanin-21 antibodyAnti-Tspan-21 antibodyAnti-Uroplakin Ia antibodyAnti-Upia antibodyAnti-Upka antibodyAnti-UPK1A TSPAN21 antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
O00322 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Alternative splicing results in multiple transcript variants of this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 110-230 of human UPK1A (NP_008931. 1). |
Short Description |
Rabbit polyclonal against UPK1A |
Tissue specificity |
High expression restricted to ureteric urothelium (most superficial cells).low expression in prostate. Expression in normal urothelial cells is lost in culture. Some expression in tumor cell lines derived from urothelial malignancies. |
Cellular localization |
MembraneMulti-Pass Membrane Protein |
Molecular weight |
Calculated: 28kDa/30kDa. Observed: 29kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Uroplakin-1a antibodyAnti-Up1a antibodyAnti-Tetraspanin-21 antibodyAnti-Tspan-21 antibodyAnti-Uroplakin Ia antibodyAnti-Upia antibodyAnti-Upka antibodyAnti-UPK1A TSPAN21 antibody |
Protein name |
Uroplakin-1aUp1aTetraspanin-21Tspan-21Uroplakin IaUpiaUpka |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.