Item no. |
STJ96789-100 |
Manufacturer |
St John's Laboratory
|
Amount |
100ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF, ELISA, IHC-P |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Heat Shock 70 Kda Protein 1a antibody</br>Anti-Heat Shock 70 Kda Protein 1 antibody</br>Anti-Hsp70-1 antibody</br>Anti-Hsp70.1 antibody</br>Anti-HSPA1A HSP72 HSPA1 HSX70 antibody |
Similar products |
Anti-Heat Shock 70 Kda Protein 1a antibodyAnti-Heat Shock 70 Kda Protein 1 antibodyAnti-Hsp70-1 antibodyAnti-Hsp70.1 antibodyAnti-HSPA1A HSP72 HSPA1 HSX70 antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Uniprot ID |
P08107 |
Storage |
Store at-20° C, and avoid repeat freeze-thaw cycles. |
Concentration |
1 mg/ml |
Description |
HSP70 is encoded by the HSPA gene family which includes many variants of the gene. It is approximately 70kDa. There are numerous members of the HSP70 heat shock protein. HSP70 is localised to the cytoplasm. It colocalizes with SHCBP1L at spindle during the meiosis process. HSP70 is a molecular chaperone that is implicated in a wide variety of cellular processes such as the quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. It is also considered a cellular thermometer in response to heat stress and other stimuli. HSP70 is expressed in nearly every cellular compartment in eukaryotes. Mutations in the HSPA gene result in protein folding disorders, autoimmune diseases and cancer. STJ96789 was developed from clone 3G10. The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody binds endogenous HSP70. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Synthesized peptide derived from human HSP70 around the non-acetylation site of K246. |
Short Description |
Rabbit polyclonal against HSP70 |
Cellular localization |
CytoplasmNucleusCytoskeletonMicrotubule Organizing CenterCentrosomeLocalized In Cytoplasmic Mrnp Granules Containing Untranslated Mrnas |
Molecular weight |
70 kDa |
Dilution range |
IF 1:50-200WB 1:500-1:2000IHC-p 1:100-1:300ELISA 1:20000 |
Alternative names |
Anti-Heat Shock 70 Kda Protein 1a antibodyAnti-Heat Shock 70 Kda Protein 1 antibodyAnti-Hsp70-1 antibodyAnti-Hsp70.1 antibodyAnti-HSPA1A HSP72 HSPA1 HSX70 antibody |
Protein name |
Heat Shock 70 Kda Protein 1aHeat Shock 70 Kda Protein 1Hsp70-1Hsp70.1 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.