Anti-Cryopyrin antibody

Polyclonal

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Q96P20

1 mg/ml

114548

Synthesized peptide derived from human Cryopyrin.

Rabbit polyclonal against Cryopyrin

Cytoplasm
Cytosol
Inflammasome
Endoplasmic Reticulum
Secreted
Nucleus
In Macrophages
Under Resting Conditions
Mainly Located In The Cytosol
On The Endoplasmic Reticulum
After Stimulation With Inducers Of The Nlrp3 Inflammasome
Mitochondria Redistribute In The Vicinity Of The Endoplasmic Reticulum In The Perinuclear Region
Which Results In Colocalization Of Nlrp3 On The Endoplasmic Reticulum And Pycard On Mitochondria
Allowing The Activation Of Inflammasome Assembly
After The Induction Of Pyroptosis
Inflammasome Specks Are Released Into The Extracellular Space Where They Can Further Promote Il1b Processing And Where They Can Be Engulfed By Macrophages
Phagocytosis Induces Lysosomal Damage And Inflammasome Activation In The Recipient Cells
In The Th2 Subset Of Cd4(+) Helper T-Cells
Mainly Located In The Nucleus
Nuclear Localization Depends Upon Kpna2
In The Th1 Subset Of Cd4(+) Helper T-Cells
Mainly Cytoplasmic (By Similarity)
Golgi Apparatus Membrane
(Microbial Infection) Upon Hrsv Infection
The Protein Is Mainly Located In Lipid Rafts In The Golgi Membrane

WB 1:500-1:2000
IHC-p 1:100-1:300
ELISA 1:20000

Nacht-Lrr And Pyd Domains-Containing Protein 3
Angiotensin/Vasopressin Receptor Aii/Avp-Like
Caterpiller Protein 1.1
Clr1.1
Cold-Induced Autoinflammatory Syndrome 1 Protein
Cryopyrin
Pyrin-Containing Apaf1-Like Protein 1

NLRP3_HUMAN