Item no. |
STJ91881-200 |
Manufacturer |
St John's Laboratory
|
Amount |
200ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Breast Cancer Type 1 Susceptibility Protein antibody</br>Anti-Ring Finger Protein 53 antibody</br>Anti-Ring-Type E3 Ubiquitin Transferase Brca1 antibody</br>Anti-BRCA1 RNF53 antibody |
Similar products |
Anti-Breast Cancer Type 1 Susceptibility Protein antibodyAnti-Ring Finger Protein 53 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Brca1 antibodyAnti-BRCA1 RNF53 antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Uniprot ID |
P38398 |
Storage |
Store at-20° C, and avoid repeat freeze-thaw cycles. |
Concentration |
1 mg/ml |
Description |
Rabbit polyclonal to BRCA1. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Synthesized peptide derived from human BRCA1 around the non-phosphorylation site of S1457. |
Immunogen region |
1400-1480 aa |
Short Description |
Rabbit polyclonal against BRCA1 |
Tissue specificity |
Isoform 1 and isoform 3 are widely expressed. Isoform 3 is reduced or absent in several breast and ovarian cancer cell lines. |
Cellular localization |
NucleusChromosomeCytoplasmLocalizes At Sites Of Dna Damage At Double-Strand Breaks (Dsbs)Recruitment To Dna Damage Sites Is Mediated By Abraxas1 And The Brca1-A Complex Translocated To The Cytoplasm During Uv-Induced Apoptosis Isoform 3: CytoplasmIsoform 5: Cytoplasm |
Molecular weight |
180 kDa |
Dilution range |
WB 1:500-1:2000ELISA 1:5000 |
Alternative names |
Anti-Breast Cancer Type 1 Susceptibility Protein antibodyAnti-Ring Finger Protein 53 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Brca1 antibodyAnti-BRCA1 RNF53 antibody |
Protein name |
Breast Cancer Type 1 Susceptibility ProteinRing Finger Protein 53Ring-Type E3 Ubiquitin Transferase Brca1 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.