Item no. |
STJ28000-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Pleckstrin Homology-Like Domain Family A Member 2 antibody</br>Anti-Beckwith-Wiedemann Syndrome Chromosomal Region 1 Candidate Gene C Protein antibody</br>Anti-Imprinted In Placenta And Liver Protein antibody</br>Anti-Tumor-Suppressing Stf Cdna 3 Pro |
Similar products |
Anti-Pleckstrin Homology-Like Domain Family A Member 2 antibodyAnti-Beckwith-Wiedemann Syndrome Chromosomal Region 1 Candidate Gene C Protein antibodyAnti-Imprinted In Placenta And Liver Protein antibodyAnti-Tumor-Suppressing Stf Cdna 3 Pro |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q53GA4 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene is located in a cluster of imprinted genes on chromosome 11p15. 5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human PHLDA2 (NP_003302. 1). |
Short Description |
Rabbit polyclonal against PHLDA2 |
Tissue specificity |
Expressed in placenta and adult prostate gland. In placenta, it is present in all cells of the villous cytotrophoblast. The protein is absent in cells from hydatidiform moles. Hydatidiform mole is a gestation characterized by abnormal development of both fetus and trophoblast. The majority of hydatidiform moles are associated with an excess of paternal to maternal genomes and are likely to result from the abnormal expression of imprinted genes (at protein level). Expressed at low levels in adult liver and lung, and fetal liver. Expressed in adult brain and neuroblastoma, medullablastoma and glioblastoma cell lines. |
Cellular localization |
CytoplasmMembranePeripheral Membrane Protein |
Molecular weight |
Calculated: 17kDa. Observed: 20kDa |
Dilution range |
WB 1:500-1:2000 IF 1:20-1:100 |
Alternative names |
Anti-Pleckstrin Homology-Like Domain Family A Member 2 antibodyAnti-Beckwith-Wiedemann Syndrome Chromosomal Region 1 Candidate Gene C Protein antibodyAnti-Imprinted In Placenta And Liver Protein antibodyAnti-Tumor-Suppressing Stf Cdna 3 Protein antibodyAnti-Tumor-Suppressing Subchromosomal Transferable Fragment Candidate Gene 3 Protein antibodyAnti-P17-Beckwith-Wiedemann Region 1 C antibodyAnti-P17-Bwr1c antibodyAnti-PHLDA2 BWR1C HLDA2 IPL TSSC3 antibody |
Protein name |
Pleckstrin Homology-Like Domain Family A Member 2Beckwith-Wiedemann Syndrome Chromosomal Region 1 Candidate Gene C ProteinImprinted In Placenta And Liver ProteinTumor-Suppressing Stf Cdna 3 ProteinTumor-Suppressing Subchromosomal Transferable Fragment Candidate Gene 3 ProteinP17-Beckwith-Wiedemann Region 1 CP17-Bwr1c |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.