Item no. |
STJ27634-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Hla Class Ii Histocompatibility Antigen Gamma Chain antibody</br>Anti-Hla-Dr Antigens-Associated Invariant Chain antibody</br>Anti-Ia Antigen-Associated Invariant Chain antibody</br>Anti-Ii antibody</br>Anti-P33 antibody</br>Anti-Cd Antigen Cd74 Clea |
Similar products |
Anti-Hla Class Ii Histocompatibility Antigen Gamma Chain antibodyAnti-Hla-Dr Antigens-Associated Invariant Chain antibodyAnti-Ia Antigen-Associated Invariant Chain antibodyAnti-Ii antibodyAnti-P33 antibodyAnti-Cd Antigen Cd74 Clea |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P04233 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 73-232 of human CD74 (NP_004346. 1). |
Short Description |
Rabbit polyclonal against CD74 |
Cellular localization |
Cell MembraneSingle-Pass Type Ii Membrane ProteinEndoplasmic Reticulum MembraneGolgi ApparatusTrans-Golgi NetworkEndosomeLysosomeTransits Through A Number Of Intracellular Compartments In The Endocytic PathwayIt Can Either Undergo Proteolysis Or Reach The Cell Membrane |
Molecular weight |
Calculated: 18kDa/26kDa/33kDa. Observed: 34kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:200 |
Alternative names |
Anti-Hla Class Ii Histocompatibility Antigen Gamma Chain antibodyAnti-Hla-Dr Antigens-Associated Invariant Chain antibodyAnti-Ia Antigen-Associated Invariant Chain antibodyAnti-Ii antibodyAnti-P33 antibodyAnti-Cd Antigen Cd74 Cleaved Into-Class-Ii-Associated Invariant Chain Peptide antibodyAnti-Clip antibodyAnti-CD74 DHLAG antibody |
Protein name |
Hla Class Ii Histocompatibility Antigen Gamma ChainHla-Dr Antigens-Associated Invariant ChainIa Antigen-Associated Invariant ChainIiP33Cd Antigen Cd74 Cleaved Into-Class-Ii-Associated Invariant Chain PeptideClip |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.