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Anti-PIEZO1 antibody

Anti-PIEZO1 antibody

Item no.	STJ26627-50
Manufacturer	St John's Laboratory
Amount	50ul
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Piezo-Type Mechanosensitive Ion Channel Component 1 antibody</br>Anti-Membrane Protein Induced By Beta-Amyloid Treatment antibody</br>Anti-Mib antibody</br>Anti-Protein Fam38a antibody</br>Anti-PIEZO1 FAM38A KIAA0233 antibody
Similar products	Anti-Piezo-Type Mechanosensitive Ion Channel Component 1 antibody Anti-Membrane Protein Induced By Beta-Amyloid Treatment antibody Anti-Mib antibody Anti-Protein Fam38a antibody Anti-PIEZO1 FAM38A KIAA0233 antibody
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	Q92508
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The protein encoded by this gene is a mechanically-activated ion channel that links mechanical forces to biological signals. The encoded protein contains 36 transmembrane domains and functions as a homotetramer. Defects in this gene have been associated with dehydrated hereditary stomatocytosis.
Gene ID	9780
Gene symbol	PIEZO1
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 2230-2420 of human PIEZO1 (NP_001136336. 2).
Short Description	Rabbit polyclonal against PIEZO1
Tissue specificity	Expressed in numerous tissues. In normal brain, expressed exclusively in neurons, not in astrocytes. In Alzheimer disease brains, expressed in about half of the activated astrocytes located around classical senile plaques. In Parkinson disease substantia nigra, not detected in melanin-containing neurons nor in activated astrocytes. Expressed in erythrocytes (at protein level).
Cellular localization	Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Cell Membrane Cell Projection Lamellipodium Membrane In Erythrocytes Located In The Plasma Membrane Accumulates At The Leading Apical Lamellipodia Of Endothelial Cells In Response To Shear Stress
Molecular weight	Calculated: 286kDa. Observed: 300kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Piezo-Type Mechanosensitive Ion Channel Component 1 antibody Anti-Membrane Protein Induced By Beta-Amyloid Treatment antibody Anti-Mib antibody Anti-Protein Fam38a antibody Anti-PIEZO1 FAM38A KIAA0233 antibody
Protein name	Piezo-Type Mechanosensitive Ion Channel Component 1 Membrane Protein Induced By Beta-Amyloid Treatment Mib Protein Fam38a
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	PIEZ1_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

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Delivery expected until 9/6/2024

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