Anti-CCNH antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P51946

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.

CCNH

Rabbit polyclonal against CCNH

Calculated: 37kDa. Observed: 36kDa

Anti-Cyclin-H antibody
Anti-Mo15-Associated Protein antibody
Anti-P34 antibody
Anti-P37 antibody
Anti-CCNH antibody

FOR RESEARCH USE ONLY (RUO).