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Anti-Phospho-RB1-(S811) antibody

Anti-Phospho-RB1-(S811) antibody

Item no.	STJ22370-50
Manufacturer	St John's Laboratory
Amount	50ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Western Blot Immunofluorescence Senescence Primary Antibodies Astrocytoma By Organ Bladder Cancer Head & Neck Cancer Bone Cancer
Type	Antibody Polyclonal
Applications	WB, IF
Specific against	Human
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Retinoblastoma-Associated Protein antibody</br>Anti-P105-Rb antibody</br>Anti-P110-Rb1 antibody</br>Anti-Prb antibody</br>Anti-Rb antibody</br>Anti-Pp110 antibody</br>Anti-RB1 antibody
Similar products	Anti-Retinoblastoma-Associated Protein antibody Anti-P105-Rb antibody Anti-P110-Rb1 antibody Anti-Prb antibody Anti-Rb antibody Anti-Pp110 antibody Anti-RB1 antibody
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P06400
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Gene ID	5925
Gene symbol	RB1
Immunogen	A phospho specific peptide corresponding to residues surrounding S811 of human RB
Short Description	Rabbit polyclonal against Phospho-RB1-(S811)
Tissue specificity	Expressed in the retina. Expressed in foreskin keratinocytes (at protein level).
Cellular localization	Nucleus During Keratinocyte Differentiation Acetylation By Kat2b/Pcaf Is Required For Nuclear Localization
Molecular weight	Calculated: 106kDa. Observed: 106kDa
Dilution range	WB 1:1000-1:2000 IF 1:50-1:100
Alternative names	Anti-Retinoblastoma-Associated Protein antibody Anti-P105-Rb antibody Anti-P110-Rb1 antibody Anti-Prb antibody Anti-Rb antibody Anti-Pp110 antibody Anti-RB1 antibody
Protein name	Retinoblastoma-Associated Protein P105-Rb P110-Rb1 Prb Rb Pp110
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	RB_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

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Delivery expected until 9/6/2024

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