Item no. |
STJ117563-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Arf Gtpase-Activating Protein Git2 antibody</br>Anti-Arf Gap Git2 antibody</br>Anti-Cool-Interacting Tyrosine-Phosphorylated Protein 2 antibody</br>Anti-Cat-2 antibody</br>Anti-Cat2 antibody</br>Anti-G Protein-Coupled Receptor Kinase-Interactor 2 ant |
Similar products |
Anti-Arf Gtpase-Activating Protein Git2 antibodyAnti-Arf Gap Git2 antibodyAnti-Cool-Interacting Tyrosine-Phosphorylated Protein 2 antibodyAnti-Cat-2 antibodyAnti-Cat2 antibodyAnti-G Protein-Coupled Receptor Kinase-Interactor 2 ant |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q14161 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 450-510 of human GIT2 (NP_476511. 1). |
Short Description |
Rabbit polyclonal against GIT2 |
Molecular weight |
Calculated: 52kDa, 70-84kDa. Observed: 84kDa |
Dilution range |
WB 1:200-1:2000 |
Alternative names |
Anti-Arf Gtpase-Activating Protein Git2 antibodyAnti-Arf Gap Git2 antibodyAnti-Cool-Interacting Tyrosine-Phosphorylated Protein 2 antibodyAnti-Cat-2 antibodyAnti-Cat2 antibodyAnti-G Protein-Coupled Receptor Kinase-Interactor 2 antibodyAnti-Grk-Interacting Protein 2 antibodyAnti-GIT2 KIAA0148 antibody |
Protein name |
Arf Gtpase-Activating Protein Git2Arf Gap Git2Cool-Interacting Tyrosine-Phosphorylated Protein 2Cat-2Cat2G Protein-Coupled Receptor Kinase-Interactor 2Grk-Interacting Protein 2 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.