Item no. |
STJ116010-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
IF |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Hyaluronidase-3 antibody</br>Anti-Hyal-3 antibody</br>Anti-Hyaluronoglucosaminidase-3 antibody</br>Anti-Lung Carcinoma Protein 3 antibody</br>Anti-Luca-3 antibody</br>Anti-HYAL3 LUCA3 antibody |
Similar products |
Anti-Hyaluronidase-3 antibodyAnti-Hyal-3 antibodyAnti-Hyaluronoglucosaminidase-3 antibodyAnti-Lung Carcinoma Protein 3 antibodyAnti-Luca-3 antibodyAnti-HYAL3 LUCA3 antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
O43820 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21. 3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 198-417 of human HYAL3 (NP_003540. 2). |
Short Description |
Rabbit polyclonal against HYAL3 |
Tissue specificity |
Expressed in sperm. Highly expressed in epidermis of the skin, where it is expressed intracellularily in the deep horny layer (at protein level). Bone marrow, testis and kidney. |
Cellular localization |
SecretedCell MembraneCytoplasmic VesicleSecretory VesicleAcrosomeEndoplasmic ReticulumEarly EndosomeMostly Present In Low-Density VesiclesLow Levels In Higher Density Vesicles Of Late Endosomes And LysosomesLocalized In Punctate Cytoplasmic Vesicles And In Perinuclear StructuresBut Does Not Colocalize With Lamp1Localized On The Plasma Membrane Over The Acrosome And On The Surface Of The Midpiece Of The Sperm Tail |
Molecular weight |
Calculated: 15kDa/18kDa/43kDa/46kDa. Observed: |
Dilution range |
IF 1:50-1:100 |
Alternative names |
Anti-Hyaluronidase-3 antibodyAnti-Hyal-3 antibodyAnti-Hyaluronoglucosaminidase-3 antibodyAnti-Lung Carcinoma Protein 3 antibodyAnti-Luca-3 antibodyAnti-HYAL3 LUCA3 antibody |
Protein name |
Hyaluronidase-3Hyal-3Hyaluronoglucosaminidase-3Lung Carcinoma Protein 3Luca-3 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.