Anti-IL12B antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P29460

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.

IL12B

Rabbit polyclonal against IL12B

Calculated: 37kDa. Observed: 37kDa

Anti-Interleukin-12 Subunit Beta antibody
Anti-Il-12b antibody
Anti-Cytotoxic Lymphocyte Maturation Factor 40 Kda Subunit antibody
Anti-Clmf P40 antibody
Anti-Il-12 Subunit P40 antibody
Anti-Nk Cell Stimulatory Factor Chain 2 antibody
Anti-Nksf2 antibody
Anti-IL12B NKSF2 antibody

FOR RESEARCH USE ONLY (RUO).