Anti-NFKB1 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P19838

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra-and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.

NFKB1

Rabbit polyclonal against NFKB1

Calculated: 85kDa/105kDa. Observed: 120kDa

Anti-Nuclear Factor Nf-Kappa-B P105 Subunit antibody
Anti-Dna-Binding Factor Kbf1 antibody
Anti-Ebp-1 antibody
Anti-Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1 Cleaved Into-Nuclear Factor Nf-Kappa-B P50 Subunit antibody
Anti-NFKB1 antibody

FOR RESEARCH USE ONLY (RUO).