« Back
Home /
Anti-SCN8A antibody

Anti-SCN8A antibody

Item no.	STJ112047-50
Manufacturer	St John's Laboratory
Amount	50ul
Category	Antibodies Western Blot Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Sodium Channel Protein Type 8 Subunit Alpha antibody</br>Anti-Sodium Channel Protein Type Viii Subunit Alpha antibody</br>Anti-Voltage-Gated Sodium Channel Subunit Alpha Nav1.6 antibody</br>Anti-SCN8A MED antibody
Similar products	Anti-Sodium Channel Protein Type 8 Subunit Alpha antibody Anti-Sodium Channel Protein Type Viii Subunit Alpha antibody Anti-Voltage-Gated Sodium Channel Subunit Alpha Nav1.6 antibody Anti-SCN8A MED antibody
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	Q9UQD0
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.
Gene ID	6334
Gene symbol	SCN8A
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1350-1440 of human SCN8A (NP_055006. 1).
Short Description	Rabbit polyclonal against SCN8A
Tissue specificity	Expressed in the hippocampus with increased expression in epileptic tissue compared to normal adjacent tissue (at protein level). Isoform 5: Expressed in non-neuronal tissues, such as monocytes/macrophages.
Cellular localization	Cell Membrane Multi-Pass Membrane Protein Cell Projection Axon Mainly Localizes To The Axon Initial Segment Isoform 5: Cytoplasmic Vesicle Some Vesicles Are Localized Adjacent To Melanoma Invadopodia And Macrophage Podosomes Does Not Localize To The Plasma Membrane
Molecular weight	Calculated: 145kDa/220kDa/225kDa/226kDa. Observed: 165kDa
Dilution range	WB 1:200-1:1000
Alternative names	Anti-Sodium Channel Protein Type 8 Subunit Alpha antibody Anti-Sodium Channel Protein Type Viii Subunit Alpha antibody Anti-Voltage-Gated Sodium Channel Subunit Alpha Nav1.6 antibody Anti-SCN8A MED antibody
Protein name	Sodium Channel Protein Type 8 Subunit Alpha Sodium Channel Protein Type Viii Subunit Alpha Voltage-Gated Sodium Channel Subunit Alpha Nav1.6
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	SCN8A_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 50ul

available

Delivery expected until 8/23/2024

Express Delivery: Save 10 days

Compare

Add to wishlist

Recommend by mail