Item no. |
STJ111318-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Erbin antibody</br>Anti-Densin-180-Like Protein antibody</br>Anti-Erbb2-Interacting Protein antibody</br>Anti-Protein Lap2 antibody</br>Anti-ERBIN ERBB2IP KIAA1225 LAP2 antibody |
Similar products |
Anti-Erbin antibodyAnti-Densin-180-Like Protein antibodyAnti-Erbb2-Interacting Protein antibodyAnti-Protein Lap2 antibodyAnti-ERBIN ERBB2IP KIAA1225 LAP2 antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q96RT1 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1152-1371 of human ERBB2IP (NP_061165. 1). |
Short Description |
Rabbit polyclonal against ERBB2IP |
Tissue specificity |
Highly expressed in brain, heart, kidney, muscle and stomach, followed by liver, spleen and intestine. |
Cellular localization |
Cell JunctionHemidesmosomeNucleus MembraneBasolateral Cell MembraneFound In HemidesmosomesWhich Are Cell-Substrate Adhesion Complexes In Stratified EpitheliaIn Transfected CellsEither Diffusely Distributed Over The Cytoplasm Or Concentrated At The Basolateral MembraneColocalizes With The Adrenergic ReceptorsAdren1a And Adren1bAt The Nuclear Membrane Of Cardiac Myocytes |
Molecular weight |
Calculated: 146-159kDa. Observed: 182kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Erbin antibodyAnti-Densin-180-Like Protein antibodyAnti-Erbb2-Interacting Protein antibodyAnti-Protein Lap2 antibodyAnti-ERBIN ERBB2IP KIAA1225 LAP2 antibody |
Protein name |
ErbinDensin-180-Like ProteinErbb2-Interacting ProteinProtein Lap2 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
|
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.