Item no. |
STJ116034-100 |
Manufacturer |
St John's Laboratory
|
Amount |
100ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF, IHC |
Specific against |
Human, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Mesothelin antibody</br>Anti-Cak1 Antigen antibody</br>Anti-Pre-Pro-Megakaryocyte-Potentiating Factor Cleaved Into-Megakaryocyte-Potentiating Factor antibody</br>Anti-Mpf-Mesothelin-Cleaved Form antibody</br>Anti-MSLN MPF antibody |
Similar products |
Anti-Mesothelin antibodyAnti-Cak1 Antigen antibodyAnti-Pre-Pro-Megakaryocyte-Potentiating Factor Cleaved Into-Megakaryocyte-Potentiating Factor antibodyAnti-Mpf-Mesothelin-Cleaved Form antibodyAnti-MSLN MPF antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q13421 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 37-296 of human MSLN (NP_001170826. 1). |
Short Description |
Rabbit polyclonal against MSLN |
Tissue specificity |
Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level). |
Cellular localization |
Cell MembraneLipid-AnchorGpi-AnchorGolgi ApparatusMegakaryocyte-Potentiating Factor: SecretedIsoform 3: Secreted |
Molecular weight |
Calculated: 67kDa/68kDa/71kDa. |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100 |
Alternative names |
Anti-Mesothelin antibodyAnti-Cak1 Antigen antibodyAnti-Pre-Pro-Megakaryocyte-Potentiating Factor Cleaved Into-Megakaryocyte-Potentiating Factor antibodyAnti-Mpf-Mesothelin-Cleaved Form antibodyAnti-MSLN MPF antibody |
Protein name |
MesothelinCak1 AntigenPre-Pro-Megakaryocyte-Potentiating Factor Cleaved Into-Megakaryocyte-Potentiating FactorMpf-Mesothelin-Cleaved Form |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.