Item no. |
STJ27313-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Syntenin-1 antibody</br>Anti-Melanoma Differentiation-Associated Protein 9 antibody</br>Anti-Mda-9 antibody</br>Anti-Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 18 antibody</br>Anti-Tacip18 antibody</br>Anti-Scaffold Protein Pbp1 antibody</b |
Similar products |
Anti-Syntenin-1 antibodyAnti-Melanoma Differentiation-Associated Protein 9 antibodyAnti-Mda-9 antibodyAnti-Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 18 antibodyAnti-Tacip18 antibodyAnti-Scaffold Protein Pbp1 antibody
|
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
O00560 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. Related pseudogenes have been identified on multiple chromosomes. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human SDCBP (NP_001007068. 1). |
Short Description |
Rabbit polyclonal against SDCBP |
Tissue specificity |
Expressed in lung cancers, including adenocarcinoma, squamous cell carcinoma and small-cell carcinoma (at protein level). Widely expressed. Expressed in fetal kidney, liver, lung and brain. In adult highest expression in heart and placenta. |
Cellular localization |
Cell JunctionFocal AdhesionAdherens JunctionCell MembranePeripheral Membrane ProteinEndoplasmic Reticulum MembraneNucleusMelanosomeCytoplasmCytosolCytoskeletonSecretedExtracellular ExosomeMembrane RaftMainly Membrane-AssociatedLocalized To Adherens JunctionsFocal Adhesions And Endoplasmic ReticulumColocalized With Actin Stress FibersAlso Found In The NucleusIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage IvAssociated To The Plasma Membrane In The Presence Of Fzd7 And Phosphatidylinositol 45-Bisphosphate (Pip2) |
Molecular weight |
Calculated: 31kDa/32kDa. Observed: 32kDa |
Dilution range |
WB 1:500-1:2000 IF 1:50-1:200 |
Alternative names |
Anti-Syntenin-1 antibodyAnti-Melanoma Differentiation-Associated Protein 9 antibodyAnti-Mda-9 antibodyAnti-Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 18 antibodyAnti-Tacip18 antibodyAnti-Scaffold Protein Pbp1 antibodyAnti-Syndecan-Binding Protein 1 antibodyAnti-SDCBP MDA9 SYCL antibody |
Protein name |
Syntenin-1Melanoma Differentiation-Associated Protein 9Mda-9Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 18Tacip18Scaffold Protein Pbp1Syndecan-Binding Protein 1 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.