Item no. |
STJ27303-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Inosine-5'-Monophosphate Dehydrogenase 2 antibody</br>Anti-Imp Dehydrogenase 2 antibody</br>Anti-Impd 2 antibody</br>Anti-Impdh 2 antibody</br>Anti-Impdh-Ii antibody</br>Anti-IMPDH2 IMPD2 antibody |
Similar products |
Anti-Inosine-5'-Monophosphate Dehydrogenase 2 antibodyAnti-Imp Dehydrogenase 2 antibodyAnti-Impd 2 antibodyAnti-Impdh 2 antibodyAnti-Impdh-Ii antibodyAnti-IMPDH2 IMPD2 antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P12268 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy-and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 215-514 of human IMPDH2 (NP_000875. 2). |
Short Description |
Rabbit polyclonal against IMPDH2 |
Tissue specificity |
IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor. |
Cellular localization |
CytoplasmNucleus |
Molecular weight |
Calculated: 55kDa. Observed: 56kDa |
Dilution range |
WB 1:500-1:2000 IF 1:50-1:200 |
Alternative names |
Anti-Inosine-5'-Monophosphate Dehydrogenase 2 antibodyAnti-Imp Dehydrogenase 2 antibodyAnti-Impd 2 antibodyAnti-Impdh 2 antibodyAnti-Impdh-Ii antibodyAnti-IMPDH2 IMPD2 antibody |
Protein name |
Inosine-5'-Monophosphate Dehydrogenase 2Imp Dehydrogenase 2Impd 2Impdh 2Impdh-Ii |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.