Item no. |
STJ25677-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Eppin antibody</br>Anti-Cancer/Testis Antigen 71 antibody</br>Anti-Ct71 antibody</br>Anti-Epididymal Protease Inhibitor antibody</br>Anti-Protease Inhibitor Wap7 antibody</br>Anti-Serine Protease Inhibitor-Like With Kunitz And Wap Domains 1 antibody< |
Similar products |
Anti-Eppin antibodyAnti-Cancer/Testis Antigen 71 antibodyAnti-Ct71 antibodyAnti-Epididymal Protease Inhibitor antibodyAnti-Protease Inhibitor Wap7 antibodyAnti-Serine Protease Inhibitor-Like With Kunitz And Wap Domains 1 antibody< |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
O95925 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. The protein can inhibit human sperm motility and exhibits antimicrobial activity against E. coli, and polymorphisms in this gene are associated with male infertility. Read-through transcription also exists between this gene and the downstream WFDC6 (WAP four-disulfide core domain 6) gene. Two transcript variants encoding different isoforms have been found for this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 22-133 of human EPPIN (NP_065131. 1). |
Short Description |
Rabbit polyclonal against EPPIN |
Tissue specificity |
In testis, expressed and secreted by Sertoli cells, appearing on the surface of testicular and ejaculate spermatozoa. Expressed in the spermatogonia and the earliest preleptotene spermatocytes. In the epididymis, is expressed and secreted by epithelial cells and covers the surface of epididymal spermatozoa and ciliated epithelial cells (at protein level). Expressed specifically in epididymis and testis. Isoform 2 is expressed only in the epididymis. Weak expression is detected in myoid cells as well as spermatogenic cells. |
Cellular localization |
Isoform 1: SecretedCell SurfaceBound To The Surface Of Testicular And On The Head And Tail Of Ejaculate Spermatozoa |
Molecular weight |
Calculated: 13kDa/15kDa/20kDa. Observed: 25kDa |
Dilution range |
WB 1:500-1:2000 IF 1:50-1:200 |
Alternative names |
Anti-Eppin antibodyAnti-Cancer/Testis Antigen 71 antibodyAnti-Ct71 antibodyAnti-Epididymal Protease Inhibitor antibodyAnti-Protease Inhibitor Wap7 antibodyAnti-Serine Protease Inhibitor-Like With Kunitz And Wap Domains 1 antibodyAnti-Wap Four-Disulfide Core Domain Protein 7 antibodyAnti-EPPIN SPINLW1 WAP7 WFDC7 antibody |
Protein name |
EppinCancer/Testis Antigen 71Ct71Epididymal Protease InhibitorProtease Inhibitor Wap7Serine Protease Inhibitor-Like With Kunitz And Wap Domains 1Wap Four-Disulfide Core Domain Protein 7 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.