Item no. |
STJ25024-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF, IHC |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-1-Phosphatidylinositol 4-5-Bisphosphate Phosphodiesterase Gamma-2 antibody</br>Anti-Phosphoinositide Phospholipase C-Gamma-2 antibody</br>Anti-Phospholipase C-Iv antibody</br>Anti-Plc-Iv antibody</br>Anti-Phospholipase C-Gamma-2 antibody</br>Anti-Plc |
Similar products |
Anti-1-Phosphatidylinositol 4-5-Bisphosphate Phosphodiesterase Gamma-2 antibodyAnti-Phosphoinositide Phospholipase C-Gamma-2 antibodyAnti-Phospholipase C-Iv antibodyAnti-Plc-Iv antibodyAnti-Phospholipase C-Gamma-2 antibodyAnti-Plc |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P16885 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4, 5-bisphosphate to 1D-myo-inositol 1, 4, 5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PLCG2 (NP_002652. 2). |
Short Description |
Rabbit polyclonal against PLCG2 |
Molecular weight |
Calculated: 147kDa. Observed: 175kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:20-1:100 |
Alternative names |
Anti-1-Phosphatidylinositol 4-5-Bisphosphate Phosphodiesterase Gamma-2 antibodyAnti-Phosphoinositide Phospholipase C-Gamma-2 antibodyAnti-Phospholipase C-Iv antibodyAnti-Plc-Iv antibodyAnti-Phospholipase C-Gamma-2 antibodyAnti-Plc-Gamma-2 antibodyAnti-PLCG2 antibody |
Protein name |
1-Phosphatidylinositol 4-5-Bisphosphate Phosphodiesterase Gamma-2Phosphoinositide Phospholipase C-Gamma-2Phospholipase C-IvPlc-IvPhospholipase C-Gamma-2Plc-Gamma-2 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
|
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.