Anti-NFATC2 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Q13469

This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.

NFATC2

Rabbit polyclonal against NFATC2

Cytoplasm
Nucleus
Cytoplasmic For The Phosphorylated Form And Nuclear After Activation That Is Controlled By Calcineurin-Mediated Dephosphorylation
Rapid Nuclear Exit Of Nfatc Is Thought To Be One Mechanism By Which Cells Distinguish Between Sustained And Transient Calcium Signals
The Subcellular Localization Of Nfatc Plays A Key Role In The Regulation Of Gene Transcription

WB 1:500-1:1000

Nuclear Factor Of Activated T-Cells-Cytoplasmic 2
Nf-Atc2
Nfatc2
Nfat Pre-Existing Subunit
Nf-Atp
T-Cell Transcription Factor Nfat1

NFAC2_HUMAN