Item no. |
STJ24752-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Nuclear Factor Of Activated T-Cells-Cytoplasmic 2 antibody</br>Anti-Nf-Atc2 antibody</br>Anti-Nfatc2 antibody</br>Anti-Nfat Pre-Existing Subunit antibody</br>Anti-Nf-Atp antibody</br>Anti-T-Cell Transcription Factor Nfat1 antibody</br>Anti-NFATC2 NFA |
Similar products |
Anti-Nuclear Factor Of Activated T-Cells-Cytoplasmic 2 antibodyAnti-Nf-Atc2 antibodyAnti-Nfatc2 antibodyAnti-Nfat Pre-Existing Subunit antibodyAnti-Nf-Atp antibodyAnti-T-Cell Transcription Factor Nfat1 antibodyAnti-NFATC2 NFA |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q13469 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. |
Gene ID |
|
Gene symbol |
|
Immunogen |
A synthetic peptide of human NFATC2 |
Short Description |
Rabbit polyclonal against NFATC2 |
Tissue specificity |
Expressed in thymus, spleen, heart, testis, brain, placenta, muscle and pancreas. Isoform 1 is highly expressed in the small intestine, heart, testis, prostate, thymus, placenta and thyroid. Isoform 3 is highly expressed in stomach, uterus, placenta, trachea and thyroid. |
Cellular localization |
CytoplasmNucleusCytoplasmic For The Phosphorylated Form And Nuclear After Activation That Is Controlled By Calcineurin-Mediated DephosphorylationRapid Nuclear Exit Of Nfatc Is Thought To Be One Mechanism By Which Cells Distinguish Between Sustained And Transient Calcium SignalsThe Subcellular Localization Of Nfatc Plays A Key Role In The Regulation Of Gene Transcription |
Molecular weight |
Calculated: 76kDa/97kDa/98kDa/99kDa/100kDa. Observed: 130kDa |
Dilution range |
WB 1:500-1:1000 |
Alternative names |
Anti-Nuclear Factor Of Activated T-Cells-Cytoplasmic 2 antibodyAnti-Nf-Atc2 antibodyAnti-Nfatc2 antibodyAnti-Nfat Pre-Existing Subunit antibodyAnti-Nf-Atp antibodyAnti-T-Cell Transcription Factor Nfat1 antibodyAnti-NFATC2 NFAT1 NFATP antibody |
Protein name |
Nuclear Factor Of Activated T-Cells-Cytoplasmic 2Nf-Atc2Nfatc2Nfat Pre-Existing SubunitNf-AtpT-Cell Transcription Factor Nfat1 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.