Item no. |
STJ191876-200 |
Manufacturer |
St John's Laboratory
|
Amount |
200ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, ELISA |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Integrin beta-1-binding protein 1 </br> Integrin cytoplasmic domain-associated protein 1 </br> ICAP-1 |
Similar products |
Integrin beta-1-binding protein 1 Integrin cytoplasmic domain-associated protein 1 ICAP-1 |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Purification |
ITBP1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Uniprot ID |
O14713 |
Storage |
Store at-20° C, and avoid repeat freeze-thaw cycles. |
Concentration |
1 mg/ml |
Description |
Unconjugated Rabbit polyclonal to ITBP1 |
Gene ID |
|
Gene symbol |
|
Short Description |
Rabbit polyclonal against ITBP1 |
Tissue specificity |
Expressed in endothelial cells and fibroblasts (at protein level). Ubiquitously expressed. Expressed in intestine, colon, testis, ovary, thymus, spleen and prostate. |
Cellular localization |
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton Cell membrane Cell projection, lamellipodium. Cell projection, ruffle. Nucleocytoplasmic shuttling protein. shuttles between nucleus and cytoplasm in a integrin-dependent manner. probably sequestered in the cytosol by ITGB1. Its localization is dependent on the stage of cell spreading on fibronectin. cytoplasmic in case of round cells, corresponding to the initial step of cell spreading, or nuclear in case of well spread cells. Colocalizes with ROCK1 and NME2 at beta-1 integrin engagement sites. Together with ITGB1 and NME2 is recruited to beta-1 integrin-rich peripheral ruffles and lamellipodia during initial cell spreading on fibronectin and/or collagen. |
Molecular weight |
22 kDa |
Dilution range |
WB 1:500-2000ELISA 1:5000-20000 |
Alternative names |
Integrin beta-1-binding protein 1 Integrin cytoplasmic domain-associated protein 1 ICAP-1 |
Protein name |
Integrin beta-1-binding protein 1 Integrin cytoplasmic domain-associated protein 1 ICAP-1 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.