Item no. |
STJ116026-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-A-Kinase Anchor Protein 5 antibody</br>Anti-Akap-5 antibody</br>Anti-A-Kinase Anchor Protein 79 Kda antibody</br>Anti-Akap 79 antibody</br>Anti-H21 antibody</br>Anti-Camp-Dependent Protein Kinase Regulatory Subunit Ii High Affinity-Binding Protein an |
Similar products |
Anti-A-Kinase Anchor Protein 5 antibodyAnti-Akap-5 antibodyAnti-A-Kinase Anchor Protein 79 Kda antibodyAnti-Akap 79 antibodyAnti-H21 antibodyAnti-Camp-Dependent Protein Kinase Regulatory Subunit Ii High Affinity-Binding Protein an |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P24588 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human AKAP5 (NP_004848. 3). |
Short Description |
Rabbit polyclonal against AKAP5 |
Tissue specificity |
Predominantly in the cerebral cortex and the postsynaptic densities of the forebrain, and to a lesser extent in adrenal medulla, lung and anterior pituitary. |
Cellular localization |
MembraneLipid-AnchorAssociates With Lipid Rafts |
Molecular weight |
Calculated: 47kDa. Observed: 47kDa |
Dilution range |
WB 1:500-1:2000 IF 1:50-1:200 |
Alternative names |
Anti-A-Kinase Anchor Protein 5 antibodyAnti-Akap-5 antibodyAnti-A-Kinase Anchor Protein 79 Kda antibodyAnti-Akap 79 antibodyAnti-H21 antibodyAnti-Camp-Dependent Protein Kinase Regulatory Subunit Ii High Affinity-Binding Protein antibodyAnti-AKAP5 AKAP79 antibody |
Protein name |
A-Kinase Anchor Protein 5Akap-5A-Kinase Anchor Protein 79 KdaAkap 79H21Camp-Dependent Protein Kinase Regulatory Subunit Ii High Affinity-Binding Protein |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
|
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.