Anti-XIAP antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P98170

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.

XIAP

Rabbit polyclonal against XIAP

Cytoplasm
Nucleus
Tle3 Promotes Its Nuclear Localization

WB 1:500-1:2000 IF 1:50-1:200

E3 Ubiquitin-Protein Ligase Xiap
Baculoviral Iap Repeat-Containing Protein 4
Iap-Like Protein
Ilp
Hilp
Inhibitor Of Apoptosis Protein 3
Iap-3
Hiap-3
Hiap3
Ring-Type E3 Ubiquitin Transferase Xiap
X-Linked Inhibitor Of Apoptosis Protein
X-Linked Iap

XIAP_HUMAN