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Anti-UNC13D antibody

Anti-UNC13D antibody

Item no.	STJ115107-100
Manufacturer	St John's Laboratory
Amount	100ul
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human, Mouse
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Protein Unc-13 Homolog D antibody</br>Anti-Munc13-4 antibody</br>Anti-UNC13D antibody
Similar products	Anti-Protein Unc-13 Homolog D antibody Anti-Munc13-4 antibody Anti-UNC13D antibody
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	Q70J99
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Gene ID	201294
Gene symbol	UNC13D
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 891-1090 of human UNC13D (NP_954712. 1).
Short Description	Rabbit polyclonal against UNC13D
Tissue specificity	Expressed at high levels in spleen, thymus and leukocytes. Also expressed in lung and placenta, and at very low levels in brain, heart, skeletal muscle and kidney. Expressed in cytotoxic T-lymphocytes (CTL) and mast cells.
Cellular localization	Cytoplasm Membrane Peripheral Membrane Protein Late Endosome Recycling Endosome Lysosome Colocalizes With Cytotoxic Granules At The Plasma Membrane Localizes To Endosomal Exocytic Vesicles
Molecular weight	Calculated: 41kDa/123kDa/128kDa. Observed: 123kDa
Dilution range	WB 1:1000-1:2000
Alternative names	Anti-Protein Unc-13 Homolog D antibody Anti-Munc13-4 antibody Anti-UNC13D antibody
Protein name	Protein Unc-13 Homolog D Munc13-4
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	UN13D_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 9/6/2024

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