Item no. |
STJ115054-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Apobec1 Complementation Factor antibody</br>Anti-Apobec1-Stimulating Protein antibody</br>Anti-A1CF ACF ASP antibody |
Similar products |
Anti-Apobec1 Complementation Factor antibodyAnti-Apobec1-Stimulating Protein antibodyAnti-A1CF ACF ASP antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q9NQ94 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 50-120 of human A1CF (NP_055391. 2). |
Short Description |
Rabbit polyclonal against A1CF |
Tissue specificity |
Widely expressed with highest levels in brain, liver, pancreas, colon and spleen. |
Cellular localization |
NucleusEndoplasmic ReticulumCytoplasmPredominantly Nuclear Where It Localizes To HeterochromatinAlso Cytoplasmic Where It Is Found At The Outer Surface Of The Endoplasmic ReticulumShuttles Between The Nucleus And CytoplasmMay Be Transported Into The Nucleus By The Nuclear Import Protein Tnpo2/Trn2 Or By Apobec1 |
Molecular weight |
Calculated: 55kDa/58kDa/62kDa/64kDa/65kDa. Observed: 65kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Apobec1 Complementation Factor antibodyAnti-Apobec1-Stimulating Protein antibodyAnti-A1CF ACF ASP antibody |
Protein name |
Apobec1 Complementation FactorApobec1-Stimulating Protein |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.