Item no. |
STJ114917-100 |
Manufacturer |
St John's Laboratory
|
Amount |
100ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Acetylcholine Receptor Subunit Delta antibody</br>Anti-CHRND ACHRD antibody |
Similar products |
Anti-Acetylcholine Receptor Subunit Delta antibodyAnti-CHRND ACHRD antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q07001 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 22-245 of human CHRND (NP_000742. 1). |
Short Description |
Rabbit polyclonal against CHRND |
Cellular localization |
Cell JunctionSynapsePostsynaptic Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
Molecular weight |
Calculated: 57kDa/58kDa. Observed: 59kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Acetylcholine Receptor Subunit Delta antibodyAnti-CHRND ACHRD antibody |
Protein name |
Acetylcholine Receptor Subunit Delta |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.